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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPNPEP3 All Species: 16.06
Human Site: S81 Identified Species: 35.33
UniProt: Q9NQH7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQH7 NP_071381.1 507 57034 S81 L R R H K L M S L I Q K E A Q
Chimpanzee Pan troglodytes XP_515152 507 56971 S81 L R R H K L M S L I Q K E A Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538358 507 57092 S81 L R R H K L M S L I H K E T Q
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508206 540 60603 T114 L R R H K L M T L I R K D T S
Chicken Gallus gallus XP_416240 502 56268 A81 M A L I Q K E A Q G W E G L D
Frog Xenopus laevis NP_001086945 502 56377 E81 S L I Q K E S E V L G C G T D
Zebra Danio Brachydanio rerio NP_996962 510 56616 S85 L R R Q R L A S L I E I Q A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608376 545 60861 A106 Q L M Q N I R A Y A R S F G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793902 510 57147 M82 R G R R H N L M S G I K K S M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172401 493 54963 K82 I I S S A P V K M M T D V V P
Baker's Yeast Sacchar. cerevisiae P40051 511 57971 P83 R L A E T L P P K S C V I L A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 92.9 N.A. N.A. N.A. N.A. 77.9 78.1 67 57.2 N.A. 34.3 N.A. N.A. 50.7
Protein Similarity: 100 99.6 N.A. 96.4 N.A. N.A. N.A. N.A. 86.4 88.9 82 73.3 N.A. 55.5 N.A. N.A. 68
P-Site Identity: 100 100 N.A. 86.6 N.A. N.A. N.A. N.A. 66.6 0 6.6 53.3 N.A. 0 N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 86.6 N.A. N.A. N.A. N.A. 86.6 26.6 20 80 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 37.6 34 N.A.
Protein Similarity: N.A. N.A. N.A. 57.7 54.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 10 0 10 19 0 10 0 0 0 28 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 19 % D
% Glu: 0 0 0 10 0 10 10 10 0 0 10 10 28 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 19 10 0 19 10 10 % G
% His: 0 0 0 37 10 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 10 10 10 10 0 10 0 0 0 46 10 10 10 0 0 % I
% Lys: 0 0 0 0 46 10 0 10 10 0 0 46 10 0 0 % K
% Leu: 46 28 10 0 0 55 10 0 46 10 0 0 0 19 0 % L
% Met: 10 0 10 0 0 0 37 10 10 10 0 0 0 0 10 % M
% Asn: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 10 10 0 0 0 0 0 0 10 % P
% Gln: 10 0 0 28 10 0 0 0 10 0 19 0 10 0 28 % Q
% Arg: 19 46 55 10 10 0 10 0 0 0 19 0 0 0 0 % R
% Ser: 10 0 10 10 0 0 10 37 10 10 0 10 0 10 10 % S
% Thr: 0 0 0 0 10 0 0 10 0 0 10 0 0 28 0 % T
% Val: 0 0 0 0 0 0 10 0 10 0 0 10 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _